Endocrine Abstracts

Introduction: Preeclampsia is a pregnancy-specific disease characterized by de novo development of concurrent hypertension, proteinuria and oxidative stress in the placenta. Hypoxia occurs during the development of placenta in the first trimester and is implicated in trophoblast differentiation. Last trimester of gestation, the calcium and mineral transport from mother to fetus are dramatically increased in response to the accelerated demand for bone mineralization in t...